Upfront Gross Proceeds of $5.0 Million, with Up to Approximately $9.8 Million of Additional Gross Proceeds Assuming the Cash Exercise in Full of Private Placement WarrantsWATERTOWN, Mass., June 27, 2025 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting, anti-inflammatory sinonasal implants for the treatment of chronic rhinosinusitis (CRS), today announced that it has entered into a definitive agreement for the ...

TORONTO, June 27, 2025 (GLOBE NEWSWIRE) -- Canadian Apartment Properties Real Estate Investment Trust (“CAPREIT”) (TSX:CAR.UN) announced today it will issue its financial results for the three and six months ended June 30, 2025 after markets close on: Thursday, August 7, 2025 A conference call to discuss the results will be hosted by the CAPREIT senior management team on: Friday, August 8, 2025 at 9:00 am ET The telephone numbers for the conference call are: Canadian Toll Free: +1 (833) 950-0062Internatio ...

BERKELEY HEIGHTS, N.J., June 27, 2025 (GLOBE NEWSWIRE) -- CorMedix Inc. (Nasdaq: CRMD), a biopharmaceutical company focused on developing and commercializing therapeutic products for life-threatening diseases and conditions, today announced the pricing of its previously announced underwritten public offering of 6,604,507 shares of its common stock. The total gross proceeds from the offering to the Company are expected to be approximately $85 million. In addition, CorMedix granted the underwriters a 30-day o ...

文章核心观点 - 公司宣布GTX - 102获FDA突破性疗法认定，有望加速治疗安格曼综合征的开发和审查进程，全球3期Aspire研究正在快速招募，Aurora研究预计今年下半年启动 [1][2][3] 药物GTX - 102相关情况 - GTX - 102是一种通过鞘内注射的反义寡核苷酸疗法，旨在抑制UBE3A反义转录本表达，重新激活缺陷蛋白表达 [4] - 已获FDA突破性疗法认定、孤儿药认定、罕见儿科疾病认定和快速通道认定，以及EMA孤儿药认定和PRIME认定 [4] 安格曼综合征相关情况 - 由母系UBE3A基因功能丧失引起，是一种终身神经发育障碍疾病，影响约6万人，常被误诊为自闭症或脑瘫，目前无获批疗法 [5][6] - 会导致认知、运动障碍，平衡问题和癫痫发作，患者需持续护理，无法独立生活，但症状在成年动物模型中可逆转 [6] 公司相关情况 - 是一家生物制药公司，致力于为严重罕见和超罕见遗传病患者提供新疗法，拥有多元化的获批药物和候选治疗产品组合 [7] - 由经验丰富的管理团队领导，策略基于高效的药物开发，目标是尽快为患者提供安全有效的疗法 [8] 研究进展相关情况 - 全球3期Aspire研究于2024年12月开始招募，预计招募约120名4 - 17岁确诊母系UBE3A基因完全缺失的安格曼综合征儿童 [3] - Aurora研究将评估GTX - 102在其他安格曼综合征基因型和年龄段的效果，预计2025年下半年启动 [3] 信息发布相关情况 - 除SEC文件、新闻稿和公开电话会议外，还通过投资者关系网站和社交媒体发布重要信息 [11] - 财务等信息可在投资者关系网站和领英网站获取 [11] 联系方式相关情况 - 投资者联系Joshua Higa，电话+1 - 415 - 475 - 6370，邮箱ir@ultragenyx.com [12] - 媒体联系Joey Fleury，邮箱media@ultragenyx.com [12]

NOVI, Mich., June 27, 2025 (GLOBE NEWSWIRE) -- Gentherm (NASDAQ: THRM) a global market leader of innovative thermal management and pneumatic comfort technologies, today announced the expansion of its long-standing partnership with DUOMED into France. Building on years of successful collaboration in the Benelux region, this extension marks a strategic milestone as both companies work to deliver advanced patient temperature management technologies to more clinicians and patients across Europe. Under this agre ...

ZEELAND, Mich., June 27, 2025 (GLOBE NEWSWIRE) -- Gentex Corporation (NASDAQ: GNTX) announced today the launch of PLACE, a new smart home safety system now available for online and in-store purchase through a national big-box retailer. PLACE is a suite of advanced, multi-feature smoke and carbon monoxide alarms designed to enhance home safety, comfort, and security with room-specific functionality. Gentex has been a leader in fire protection and sensing technology for over 50 years. The launch of PLACE in t ...

Dairy Based Renewable Natural Gas from Seven Digesters Averages Negative 384 Carbon IntensityCUPERTINO, Calif., June 27, 2025 (GLOBE NEWSWIRE) -- Aemetis, Inc. (NASDAQ: AMTX), a renewable natural gas (RNG) and renewable fuels company, announced today that the California Air Resources Board (CARB) has approved provisional pathways under the Low Carbon Fuel Standard (LCFS) for seven dairy digesters built and operated by Aemetis Biogas, a subsidiary of the Company. The pathway approvals are effective as of Jan ...

Frøya, 27 June 2025: The annual general meeting of Kaldvík AS was held today on 27 June 2025 at 12:00 hours (CEST) with approximately 61.24% of all shares entitled to vote present either in person or by proxy. A copy of the minutes is attached to this announcement. All resolutions were approved in accordance with the proposal from the board of directors. For further information, please contact:Roy-Tore Rikardsen, CEO: +354 791 0006 (mobile)Robert Robertsson, CFO: +354 843 0086 (mobile) This information is s ...

June 27, 2025 - 1.45 PM CETRegulated information – Contains inside information Arbitral Tribunal acting under ICC Rules of Arbitration issues final award in an arbitration between Agfa-Gevaert and the insolvency receiver of AgfaPhoto GmbH Mortsel, Belgium – June 27, 2025 – 1.45 PM CETAn Arbitral Tribunal acting under the International Chamber of Commerce (ICC) Rules of Arbitration has rendered a final award in the last arbitration proceeding with a possible material impact between Agfa-Gevaert and the i ...

Tetra-functional T-cell engagers activate T cells and simultaneously reduce immunosuppression, with potent and antigen-specific anti-pancreatic cancer activities at dose levels that are well tolerated Presentation at the Phoenix Best Science Series by HonorHealth Research Instituteon June 27, 2025 in Scottsdale, Arizona MIRAMAR, Fla., June 27, 2025 (GLOBE NEWSWIRE) -- HCW Biologics Inc. (the “Company” or “HCW Biologics”), (NASDAQ: HCWB), a U.S.-based clinical-stage biopharmaceutical company focused on disco ...