Rhythm Pharmaceuticals January 2025 © Rhythm® Pharmaceuticals, Inc. All rights reserved. Exhibit 99.2 Forward Looking Statements This presentation contains certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, ar ncertainties, including without limitation statements regarding the potential, safety, efficacy, and regulatory and clinical progress of setmel (formerly LB54640), and RM718, including the anticipated timing for initiation of clinical trials ...