As filed with the Securities and Exchange Commission on August 20, 2026 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 HCW BIOLOGICS INC. (Exact name of Registrant as specified in its charter) (State or Other Jurisdiction of Primary Standard Industrial (I.R.S. Employer Incorporation or Organization) Classification Code Number Identification Number) Delaware 2834 82-5024477 2929 N Commerce Parkway ...