纪要涉及的公司 Lantheus是一家领先的放射性药物公司，致力于寻找、对抗和跟踪疾病，以提供更好的患者治疗效果 [3]。 纪要提到的核心观点和论据 1. **市场领先产品组合** - **Polarify**：是分子成像领域的重磅产品，去年销售额达15.8亿美元，第一季度销售表现出色；是首个商业化的PSMA成像剂，拥有强大的制造网络；TAM预计每年增长15% - 20%，今年预计增长15% - 17% [6][7]。 - **Definity**：是公司多年来稳定增长的资产，第一季度销售额近8000万美元；是出色的诊断成像剂，用于使左心室腔显影或改善左心室边界的描绘；目前TAM约为每年3.5亿美元，到本十年末美国市场将达到6亿美元，未来将恢复低到中个位数增长，明年可能实现更高个位数增长 [8][9][10]。 2. **研发管线** - **阿尔茨海默病痴呆相关** - **MK6240**：是第二代tau剂，比第一代更具特异性，能更早、更清晰地检测神经原纤维缠结纤维，脱靶结合显著减少；参与全球39个学术机构的约109项学术研究，与15家制药公司建立合作关系 [14][15][16]。 - **NAV**：是第二代β - 淀粉样蛋白产品，与其他市售β - 淀粉样蛋白治疗药物相比，转换为中心体计数的能力最佳，在灰质与白质信号比和动态范围方面表现出色，能提供更清晰的图像，检测更低的中心体计数，有助于阿尔茨海默病的治疗、监测和诊断 [18][19][20]。 - **神经内分泌肿瘤相关** - **Octavy（LNTH2501）**：预计明年年中推出，TAM目前约为5万次扫描，到本十年末将增长到6万次扫描，约3亿美元；公司凭借自身优势有望在市场中占据一定份额 [23]。 - **20O3**：有望在明年年中获批并推出，市场TAM正在增长，随着向一线治疗推进和新适应症的明确，市场将进一步扩大 [24][25][26]。 - **GRPR（RM2）**：诊断剂为镓产品，治疗剂为基于镥的产品，在前列腺癌，特别是早期前列腺激素敏感性疾病中有明显表达；诊断剂处于二期阶段，计划明年初开展治疗剂的临床试验 [26][27]。 - **LLRC15**：是一种在多种恶性肿瘤中过表达并被内化的人源化抗体，计划在今年年底开展一期临床试验，一期试验将从骨肉瘤开始 [37][38]。 3. **财务与增长展望** - **2026年实现双位数增长的途径**：稳定Polarify的价格动态；剥离spec业务，释放增长潜力；推出NeuroSeq、Octavy、20O3、MK6240等产品；Definity恢复正常增长速度 [45][46]。 - **Polarify市场**：市场将持续演变，尽管年初定价调整使竞争对手获得试用机会，但因Postluma存在假阳性问题，客户开始回流；预计所有PSMA代理的平均销售价格将在近期趋于稳定 [50][51]。 其他重要但是可能被忽略的内容 - 公司正在等待南非对Life Molecular Imaging交易的批准，预计近期完成收购 [11]。 - 公司与Ratio合作参与其FAP治疗剂试验，公司的铜 - 64 FAP作为诊断剂 [39]。 - 公司即将到来的催化剂包括MK 6240在第三季度提交新药申请、明年提交NAV申请、JEPNET诊断获批并于明年年中推出、20O3可能于明年年中获批并推出等 [41]。

NASDAQ: LNTH Lantheus Investor Presentation BUILDING ON OUR FOUNDATION TO POWER THE FUTURE OF RADIOPHARMACEUTICALS 2025 Truist Securities MedTech Conference June 17, 2025 © 2025 Lantheus. All rights reserved. Safe Harbor Statements Cautionary Statement Regarding Forward-Looking Statements This document contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, that are subject to risks and uncertainties and are made pursuant to the safe harbor ...

BEDFORD, Mass., June 11, 2025 (GLOBE NEWSWIRE) -- Lantheus Holdings, Inc. (the Company) (NASDAQ: LNTH), the leading radiopharmaceutical-focused company committed to enabling clinicians to Find, Fight and Follow disease to deliver better patient outcomes, announced the presentation of new data highlighting two oncology radiodiagnostic agents will be presented at the upcoming 2025 Society of Nuclear Medicine and Molecular Imaging (SNMMI) Annual Meeting, taking place June 21-24, 2025, in New Orleans, LA. Prese ...

Lantheus (LNTH) FY Conference June 10, 2025 02:40 PM ET Speaker0 Following session is not open to the press. Okay. Speaker1 Good afternoon, everyone. I'm Paul Choi, and I cover the biotechnology sector here at the firm at Goldman Sachs. It's my pleasure to welcome Lampius. Joining me on stage to my immediate left is Brian Markinson, CEO, and Bob Marshall to my far left. What I'll do is turn it over to Brian maybe for some introductory or overview comments and then we'll get into Q and A after that. Speaker0 ...

Lantheus is the leading radiopharmaceutical-focused company, delivering life-changing science to enable clinicians to Find, Fight and Follow disease to deliver better patient outcomes. Headquartered in Massachusetts with offices in New Jersey, Canada, Sweden and Switzerland, Lantheus has been providing radiopharmaceutical solutions for nearly 70 years. For more information, visit www.lantheus.com. Contacts: Mark Kinarney Vice President, Investor Relations 978-671-8842 ir@lantheus.com Melissa Downs Executive ...

BEDFORD, Mass., June 03, 2025 (GLOBE NEWSWIRE) -- Lantheus Holdings, Inc. (“Lantheus”) (NASDAQ: LNTH), the leading radiopharmaceutical-focused company committed to enabling clinicians to Find, Fight and Follow disease to deliver better patient outcomes, today announced Brian Markison, Chief Executive Officer, will present at the Goldman Sachs 46th Annual Global Healthcare Conference 2025 at 2:40 p.m. ET on Tuesday, June 10. To access a live webcast of the presentation, please visit the Investors section of ...

Lantheus (NASDAQ: LNTH ) shares fell 25% after its Q1 2025 report. While it is never good to disappoint expectations and reduce EPS guidance for 2025, I think it is justified by M&A costs, divestitures of a low-growth segment andMy name is María Fernanda and I'm currently studying an MBA. My inspiration investors are Warren Buffett, Peter Lynch and Terry Smith, so I look for quality companies at a reasonable valuation. I believe that, in the long term, fundamentals are what drive the share price, so I look ...

LOS ANGELES, May 8, 2025 /PRNewswire/ -- The DJS Law Group announces that it is investigating claims on behalf of investors of Lantheus Holdings, Inc. ("Lantheus" or "the Company") (NASDAQ: LNTH) for violations of the securities laws. DJS Law Group INVESTIGATION DETAILS: The investigation focuses on whether the Company issued misleading statements and/or failed to disclose information pertinent to investors. Lantheus reported its financial results for the first quarter of 2025 on May 7, 2025. Along wit ...

Lantheus (LNTH) Q1 2025 Earnings Call May 07, 2025 08:00 AM ET Company Participants Mark Kinarney - VP - Investor RelationsBrian Markison - CEO & DirectorPaul Blanchfield - PresidentAmanda Morgan - Chief Commercial OfficerRobert Marshall - CFO & TreasurerAnthony Petrone - Managing DirectorRichard Newitter - Managing DirectorMatthew Taylor - Managing DirectorYuan Zhi - Managing Director Conference Call Participants Roanna Ruiz - Senior Managing Director, Biotechnology AnalystNone - AnalystLarry Solow - Partn ...

Lantheus (LNTH) Q1 2025 Earnings Call May 07, 2025 08:00 AM ET Speaker0 Good morning. Welcome to Lantheus First Quarter twenty twenty five Conference Call. All lines have been placed on mute. This call is being recorded and a replay will be available in the Investors section of the company's website approximately two hours after the completion of the call and will be archived for at least thirty days. I'll now turn the call over to Mark Kanarney, Vice President of Investor Relations. Mark? Speaker1 Thank yo ...