Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 AKARI THERAPEUTICS, PLC (Exact name of registrant as specified in its charter) England and Wales 2834 98-1034922 (State or other jurisdiction of incorporation or organization) As filed with the Securities and Exchange Commission on November 17, 2025 Washington, D.C. 20549 FORM S-1 (Primary Standard Industrial Classification Code) (I.R.S. Employer Identification No.) 401 E Jackson St ...