TABLE OF CONTENTS As filed with the Securities and Exchange Commission on January 24, 2024. Registration No. 333-276664 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Amendment No. 1 to FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Sagimet Biosciences Inc. (Exact name of registrant as specified in its charter) 2834 Delaware (State or other jurisdiction of incorporation or organization) (Primary Standard Industrial Classification Code Number) David Happel President ...