As filed with the Securities and Exchange Commission on February 5, 2026. Registration No. 333-293150 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Amendment No. 2 TO FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ERNEXA THERAPEUTICS INC. (Exact name of registrant as specified in its charter) (State or other jurisdiction of incorporation or organization) Delaware 2834 31-1103425 (Primary Standard Industrial Classification Code Number) (IRS Employer Identification ...