Exhibit 2.1 CONFIDENTIAL EXECUTION VERSION AGREEMENT AND PLAN OF MERGER DATED AS OF AUGUST 7, 2025, AMONG CORMEDIX INC., CORIANDER BIDCO LLC, MELINTA THERAPEUTICS, LLC, AND DEERFIELD PRIVATE DESIGN FUND IV, L.P., AS THE MEMBERS' REPRESENTATIVE CERTAIN IDENTIFIED INFORMATION HAS BEEN EXCLUDED FROM THIS EXHIBIT BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) PRIVATE OR CONFIDENTIAL. SUCH EXCLUDED INFORMATION IS IDENTIFIED HEREIN WITH "[***]." SCHEDULES AND EXHIBITS HAVE BEEN OMITTED PURSUANT TO ITEM 601(A)(5) OF ...