股权质押 - 吴瑞本次质押260万股，占所持6.65%，总股本0.16%[1] - 吴瑞本次质押466万股，占所持11.92%，总股本0.28%[1] - 吴瑞本次解除质押710万股，占所持18.16%，总股本0.42%[2] 股东持股 - 以岭医药科技持股526775963股，比例31.53%[3] - 吴相君持股347728119股，比例20.81%[3] - 吴瑞持股39096008股，比例2.34%[3] 综合情况 - 合计持股913600090股，比例54.68%[3] - 吴瑞已质押限售和冻结4660000股，占已质押64.19%[3] - 吴相君未质押限售和冻结260796089股，占未质押77.53%[3] - 吴瑞未质押限售和冻结24662006股，占未质押77.47%[3]