Table of Contents As filed with the U.S. Securities and Exchange Commission on October 21, 2025 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Semnur Pharmaceuticals, Inc. (Name, address, including zip code, and telephone number, including area code, of agent for service) Copies to: Jeffrey T. Hartlin, Esq. Elizabeth A. Razzano, Esq. (Exact name of registrant as specified in its charter) Paul Hast ...