Table of Contents As filed with the Securities and Exchange Commission on August 1, 2024 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 APTOSE BIOSCIENCES INC. (Exact Name of Registrant As Specified In Its Charter) (State or other jurisdiction of incorporation or organization) (Primary Standard Industrial Canada 2836 98-1136802 Classification Code Number) (I.R.S. Employer Identification Number) 66 ...