As filed with the Securities and Exchange Commission on July 25, 2025 Registration No. 333-288877 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 1 to FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 CINGULATE INC. (Primary Standard Industrial Classification Code Number) Delaware 2834 86-3825535 (I.R.S. Employer Identification Number) 1901 W. 47th Place Kansas City, KS 66205 (913) 942-2300 (Address, including zip code, and telephone number, including are ...