Table of Contents As filed with the Securities and Exchange Commission on October 6, 2025. Registration No. 333-290400 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 AMENDMENT NO. 1 TO FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 MapLight Therapeutics, Inc. (Exact name of Registrant as specified in its charter) (State or other jurisdiction of incorporation or organization) (Primary Standard Industrial Classification Code Number) 800 Chesapeake Drive Delaware 2834 ...