As filed with the Securities and Exchange Commission on May 19, 2023 Registration No. 333-269218 (I.R.S. Employer Identification No.) Kiryat Atidim, Building 7 Tel Aviv, 6158002, Israel +972-77-331-0156 (Address, including zip code, and telephone number, including area code, of registrant's principal executive offices) UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Amendment No. 5 to FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 CHEMOMAB THERAPEUTICS LTD. (Exact n ...