UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) May 12, 2025 Delaware 001-36279 75-3175693 (State or other jurisdiction of incorporation) (Commission File Number) (IRS Employer Identification No.) TVARDI THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Check the appropriate box below if the Form 8-K filing is intended ...