Exhibit 3.1 SECOND AMENDED AND RESTATED BYLAWS OF ARDELYX, INC. (a Delaware corporation) TABLE OF CONTENTS | | | Page | | --- | --- | --- | | ARTICLE | I - CORPORATE OFFICES | 1 | | 1.1 | REGISTERED OFFICE | 1 | | 1.2 | OTHER OFFICES | 1 | | ARTICLE | II - MEETINGS OF STOCKHOLDERS | 1 | | 2.1 | PLACE OF MEETINGS | 1 | | 2.2 | ANNUAL MEETING | 1 | | 2.3 | SPECIAL MEETING | 1 | | 2.4 | ADVANCE NOTICE PROCEDURES FOR BUSINESS BROUGHT BEFORE A MEETING | 2 | | 2.5 | ADVANCE NOTICE PROCEDURES FOR NOMINATIONS OF DI ...