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Cullinan Therapeutics to Present Clinical Data from Phase 1 Study Evaluating Novel Anti-MICA/B Antibody, CLN-619, as Monotherapy and in Combination with a Checkpoint Inhibitor in Patients with Advanced Solid Tumors at ASCO 2024

CLN-619介绍 - CLN-619是一种新颖的潜在一类抗体,通过多种机制发挥作用,为与检查点抑制剂等免疫疗法结合提供机会[2] - CLN-619是一种人源化IgG1单克隆抗体,结合于MICA和MICB应激诱导配体,通过多种免疫介导机制促进抗肿瘤活性[4]