Precancerous Anal Dysplasia: Phase 2 open-label trial n=24 3 or 4 dose regimen at Months 0, 1, 3 and Week 36 (optional) Final findings (6 months after start of treatment) Clearance of HPV 16/18+ lesions: 50% of patients The Spontaneous Rate is estimated to be less than 27% • VGX-3100: composed of plasmids encoding for HPV-16 and HPV-18 subtypes; E6 and E7 oncogenes • Open-label trial of VGX-3100 in 24 HIV-negative participants with HPV-16 and/or -18-positive anal HSIL • 50% (11/22 evaluable) of participants ...