Second Quarter 2025 Financial Results • Christine Akinc Chief Corporate Communications Officer Overview • Yvonne Greenstreet, M.D., MBA Chief Executive Officer Commercial Highlights • Tolga Tanguler Chief Commercial Officer July 31, 2025 © 2025 Alnylam Pharmaceuticals, Inc. 1 Agenda Welcome Pipeline • Pushkal Garg, M.D. Chief Research & Development Officer Financial Summary and Upcoming Milestones • Jeff Poulton Chief Financial Officer Q&A Session 2 Alnylam Forward Looking Statements This presentation conta ...