文章核心观点 - 公司宣布在纽约市威尔康奈尔医学院多发性硬化症中心启动2期临床试验给药，评估鼻内给药福拉珠单抗治疗非活动性继发性进展型多发性硬化症的安全性和有效性，该试验旨在满足多发性硬化症治疗中未满足的医疗需求 [1][2][3] 分组1：公司信息 - 公司是一家临床阶段生物制药公司，利用变革性药物递送技术开发突破性疗法，其创新的鼻腔给药方法相比静脉给药在疗效、安全性和耐受性上有提升潜力 [7] - 公司的领先候选药物鼻内给药福拉珠单抗是目前唯一处于临床开发阶段的全人抗CD3单克隆抗体，在既往研究中显示出良好的安全性和临床反应，公司免疫疗法替代途径技术已获专利且有多项申请待批 [7] 分组2：药物信息 - 福拉珠单抗是首个通过鼻内途径给药的全人抗CD3单克隆抗体，这种非全身性方法旨在激活调节性T细胞，促进免疫耐受同时减少全身性免疫抑制 [4] - 目前已有10名非活动性继发性进展型多发性硬化症患者在开放标签中期扩大使用计划中接受了福拉珠单抗治疗，所有患者在6个月内病情均有改善或稳定 [5] - 鼻内给药福拉珠单抗正在非活动性继发性进展型多发性硬化症患者中进行2a期随机、双盲、安慰剂对照、多中心、剂量范围试验 [5] 分组3：临床试验信息 - 2期试验旨在评估公司创新疗法治疗多发性硬化症的安全性和有效性，威尔康奈尔医学院多发性硬化症中心的加入为试验带来宝贵见解和资源 [2] - 2期试验于2023年11月开始筛选患者，完成盲法阶段后，所有参与者包括最初接受安慰剂的患者将有机会在6个月开放标签扩展阶段接受鼻内给药福拉珠单抗，以评估其长期安全性和持续益处 [3][6] - 该试验的第五个试验点是威尔康奈尔医学院多发性硬化症中心，其他试验点包括耶鲁大学、约翰霍普金斯大学、布里格姆妇女医院和马萨诸塞大学 [1]

文章核心观点 RedCloud Holdings plc首席执行官兼联合创始人Justin Floyd将参加ROTH第15届伦敦年度会议 [1] 会议信息 - 会议名称为ROTH 15 Annual London Conference [2] - 举办时间为2025年6月24 - 26日 [2] - 举办地点在英国伦敦 [2] - 形式为1对1或小组会议，仅受邀参加 [2] - 约70家不同行业公司高管将参会，机构投资者可与公司领导层深入交流 [2] - 可访问https://ibn.fm/RothLondon2025了解更多并提交注册申请 [3] ROTH介绍 - ROTH是一家以关系为导向的投资银行，服务成长型公司及其投资者 [3] - 提供包括资本筹集、股票研究、宏观经济、销售交易等全方位服务 [3] - 总部位于加州纽波特海滩，为私人持股、员工所有企业，在美国各地设有办事处 [3] - 更多信息可访问https://www.roth.com [4] RedCloud介绍 - RedCloud开发并运营RedCloud交易平台，促进快消品日常消费供应在商业供应链中的交易 [4] - 平台解决了高增长消费市场中品牌、经销商和零售商之间关键采购和销售数据获取的问题 [4] - 零售商可借助平台利用人工智能驱动的数据洞察，更轻松地进行企业对企业采购和库存决策 [4] - 更多信息可访问www.redcloudtechnology.com，也可在领英和脸书联系 [4] 联系方式 - 投资者关系联系人为首席投资官Sukhvinder Gill，邮箱Investor.relations@redcloudtechnology.com [5] - 媒体关系联系人为全球营销执行副总裁James McCarthy，邮箱media@redcloudtechnology.com [5] - 新闻专线服务联系IBN，位于德克萨斯州奥斯汀，网址www.InvestorBrandNetwork.com，电话512.354.7000，邮箱Editor@InvestorBrandNetwork.com [5]

文章核心观点 - 公司投资UAB “Ateities ūkis”以促进立陶宛原奶生产，认为交易有益且财务安全 [1] 投资情况 - 公司向UAB “Ateities ūkis”的法定资本投资1000万欧元，收购其29.67%的法定资本 [1] 被投资公司情况 - UAB “Ateities ūkis”属于Agrokoncernas集团，主要业务之一是原奶生产 [1] 公司管理层看法 - 认为该交易对公司有益，将确保立陶宛高品质原奶产量增加 [1] - 确信交易财务安全，不会对公司业绩和财务状况产生重大影响 [1]

NOT FOR DISTRIBUTION TO U.S. NEWS WIRE SERVICES OR DISSEMINATION IN THE UNITED STATES WINNIPEG, Manitoba, June 13, 2025 (GLOBE NEWSWIRE) -- (TSX: NFI, OTC: NFYEF, TSX: NFI.DB) NFI Group Inc. (NFI, or the Company) a leader in propulsion-agnostic bus and coach mobility solutions, today announced that its subsidiary, New Flyer Holdings, Inc. (the Issuer), has completed its previously announced private offering of $600 million in aggregate principal amount of 9.250% second lien senior secured notes due 2030 (th ...

SINGAPORE, June 13, 2025 (GLOBE NEWSWIRE) -- Multi Ways Holdings Limited (“Multi Ways,” the “Company” or the “Issuer”) (NYSE American: MWG), a leading supplier of a wide range of heavy construction equipment for sales and rental in Singapore and the surrounding region, announced that it has filed its annual report on Form 20-F, including its financial results, for the fiscal year ended December 31, 2024 (the “2024 Annual Report”) with the U.S. Securities and Exchange Commission. The 2024 Annual Report can b ...

Millicom (Tigo) Announces Partial Closing of Infrastructure Deal with SBA and Intention to Declare a Special Dividend of $2.50 per Share Representing Around 45% of the Proceeds Luxembourg, June 13, 2025 – Millicom International Cellular S.A. (NASDAQ: TIGO) today announced the partial closing of its previously disclosed transaction with SBA Communications Corporation (NASDAQ: SBAC), through the sale of LATI International S.A., the Luxembourg-based holding company for Millicom’s mobile passive infrastructure ...

SOUTH SAN FRANCISCO, Calif., June 13, 2025 (GLOBE NEWSWIRE) -- RAPT Therapeutics, Inc. (Nasdaq: RAPT) (the “Company”), a clinical-stage immunology-based biopharmaceutical company focused on discovering, developing and commercializing novel therapies for patients living with inflammatory and immunological diseases, today announced that a 1-for-8 reverse stock split of its outstanding shares of common stock will be effective at 11:59 pm Eastern Time June 16, 2025. Following the reverse stock split, the Compan ...

Le Mans Ultimate to Launch Full 1.0 Release on July 22, 2025, Introducing Mercedes AMG LMGT3 Evo, Aston Martin Valkyrie, and a Glimpse Into the Future Le Mans Ultimate is set to be full released on 22nd July 2025, including the Aston Martin Valkyrie AMR and the Mercedes AMG LMGT3 Evo. Additionally, the European Le Mans Series content is confirmed for the title as well as future plans for a career mode. MIAMI, June 13, 2025 (GLOBE NEWSWIRE) -- Motorsport Games Inc. (NASDAQ: MSGM) (“Motorsport Games” or “ ...

– Rademikibart significantly improved lung function and asthma control in patients with eosinophilic-driven type 2 asthma – – Rademikibart reduced annualized exacerbations in patients with eosinophilic-driven type 2 asthma – – Data supports ongoing Phase 2 acute exacerbation studies in asthma and COPD; expect to report topline data from both studies in 1H26 – SAN DIEGO, June 13, 2025 (GLOBE NEWSWIRE) -- Connect Biopharma Holdings Limited (Nasdaq: CNTB) (“Connect Biopharma” or the “Company”), a clinical-stag ...

PALO ALTO, CA, June 13, 2025 (GLOBE NEWSWIRE) -- Cloudastructure, Inc. (Nasdaq: CSAI) (“we,” “us,” “our,” “Cloudastructure” or the “Company”) a recognized leader in AI surveillance and remote guarding solutions, today announced that a leading national property management firm, with assets across 18 states, has selected the Company’s advanced AI Surveillance platform to enhance security at a prominent mixed-use community. The decision aims to address persistent security challenges affecting both residents an ...