FORWARD-LOOKING STATEMENTS Certain statements in this announcement are forward-looking statements. These forward-looking statements involve known and unknown risks and uncertainties and are based on the Company's current expectations, including the Company's ability to generate revenues from the sale of JOTROL products to consumers through the DTC model. Investors can find many (but not all) of these statements by the use of words such as "approximates," "believes," "hopes," "expects," "anticipates," "estim ...

SOUTH SAN FRANCISCO, Calif., July 10, 2025 (GLOBE NEWSWIRE) -- Maze Therapeutics, Inc. (Nasdaq: MAZE), a clinical-stage biopharmaceutical company developing small molecule precision medicines for patients with renal, metabolic and cardiovascular diseases, today announced that company management will participate in fireside chats during two upcoming investor conferences in July: H.C. Wainwright 4th Annual Kidney Virtual Conference on Monday, July 14, 2025, at 2:30 p.m. ETBTIG Virtual Biotech Conference on We ...

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This article is published by Terry Chrisomalis, who runs the Biotech Analysis Central pharmaceutical service on Seeking Alpha Marketplace. If you like what you read here and would like to subscribe to, I'm currently offering a two-week free trial period for subscribers to take advantage of. My service offers a deep-dive analysis of many pharmaceutical companies. The Biotech Analysis Central SA marketplace is $49 per month, but for those who sign up for the yearly plan will be able to take advantage of a 33. ...

CEO's personal contribution fully funds build-out and first-year operationsDoubled HQ footprint centralizes cross-functional teams, including research, regulatory affairs, and the expanding Tevogen.AI initiative WARREN, N.J., July 10, 2025 (GLOBE NEWSWIRE) -- Tevogen (“Tevogen Bio Holdings Inc.” or “Company”) (Nasdaq: TVGN) today announced the completion and official opening of its fully functional, newly expanded corporate headquarters in Warren, New Jersey. The build-out and first-year operating costs we ...

IGI Therapeutics SA, a wholly owned subsidiary of New York-based Ichnos Glenmark Innovation Inc., and AbbVie Inc. ABBV, on Thursday, announced an exclusive licensing agreement for IGI’s lead investigational asset, ISB 2001, developed using IGI’s proprietary BEAT protein platform, for oncology and autoimmune diseases.“Multispecifics including trispecific antibodies represent a new frontier in immuno-oncology with the potential to deliver deeper, more durable responses by engaging multiple targets simultaneou ...

The U.S. Food and Drug Administration (FDA) has approved Moderna Inc.'s MRNA supplemental Biologics License Application (sBLA) for Spikevax, the company's COVID-19 vaccine, in children six months through 11 years of age who are at increased risk for COVID-19 disease. The company's COVID-19 vaccine, mRNA-1273, was previously available for pediatric populations under Emergency Use Authorization. Also Read: Moderna's mRNA Flu Vaccine Outperforms Standard Shots "COVID-19 continues to pose a significant potentia ...

公司访谈发布 - Floorstocks金融媒体平台发布了对Wellgistics Health Inc首席执行官Brian Norton的独家采访 采访在纳斯达克MarketSite录制 面向120万活跃零售投资者 [1] - 采访视频已在YouTube和Floorstocks官网同步上线 展示医疗保健领域最具颠覆性的新兴成长型公司之一 [1] - 资深市场专家Kenneth Polcari主持访谈 探讨Wellgistics如何革新美国6000亿美元处方药市场 包括消除中间环节 提升透明度 加速合规配送 [1] Wellgistics商业模式 - 公司采用垂直整合技术栈 构建全国性服务网络 AI驱动的基础设施支持药房 供应商 制造商和雇主集团 [2] - 平台覆盖批发分销 数字化处方路由 以及资格审核 事前授权 用药依从性和直达患者配送等枢纽服务 [5] - 作为PBM替代方案 但保持PBM中立 为产业链各环节提供透明端到端药品接入服务 [5] 战略愿景 - 首席执行官Brian Norton强调通过透明化建立信任 提出用可扩展解决方案修复当前医疗系统缺陷的愿景 [3] - 公司正扩大直接分销网络 拓展雇主专项计划 加码技术驱动的合规药房解决方案 [3] - 此次访谈是投资者教育计划的一部分 旨在提升机构对Wellgistics的认知度 [3] 行业背景 - 美国处方药市场规模超过6000亿美元 存在系统性低效问题 Wellgistics瞄准该市场进行颠覆性创新 [1][2] - 医疗保健行业面临中间环节冗余 透明度不足 配送效率低下等痛点 需要技术驱动的解决方案 [1][2] 媒体合作 - Floorstocks专注于连接高成长上市公司与新一代投资者 通过跨平台内容分发重塑公开市场传播方式 [4] - 本次访谈属于付费投资者认知活动 Wellgistics支付7.5万美元费用 但内容制作保持独立编辑控制权 [6][7]

药物研发进展 - Ultragenyx Pharmaceutical (RARE) 和 Mereo BioPharma (MREO) 更新了中后期Orbit研究的进展 该研究评估UX143 (setrusumab) 用于治疗儿童和年轻成人成骨不全症(OI) 目前III期部分按原计划将于2025年底完成最终分析 而非公司此前希望的提前终止研究 [1] - UX143是一种全人源单克隆抗体 可抑制硬化蛋白 独立数据监测委员会审查中期安全性数据后认为UX143安全性可接受 建议研究按计划推进至最终分析 [2] - 虽然III期Cosmic研究数据未在本次中期审查中评估 但两项研究均进展顺利 反馈显示UX143治疗可能增加骨量 从而增强骨骼强度 减少骨折并改善身体功能 [3] 临床试验设计 - Orbit研究旨在评估UX143对5-25岁OI患者骨折率的影响 II期24名患者随机接受两种剂量 确定20 mg/kg为III期最佳剂量 III期部分纳入159名患者 按2:1随机分配至UX143或安慰剂组 主要终点为降低年化临床骨折率 [7] - Cosmic研究针对2-7岁患者 比较UX143与静脉双膦酸盐的骨折减少效果 已纳入69名患者 [8] - 两项研究的最终分析将在患者完成至少18个月治疗后进行 [4] 商业合作与市场 - Ultragenyx与Mereo于2020年签署许可协议 共同开发UX143 RARE拥有美国 土耳其及其他非欧洲经济区 英国和瑞士地区的独家开发和商业化权利 MREO保留上述除外地区的权利 [9] - 2024年双方扩大合作 签订制造和供应协议 RARE负责向MREO辖区供应setrusumab MREO将承担部分开发和未来供应成本 [9] - OI是一种影响骨骼代谢的遗传性疾病 在商业可及地区影响约6万人 目前尚无获批疗法 [11] 市场表现 - 由于推迟Orbit研究新数据至年底 RARE和MREO股价在盘前大幅下跌 年初至今 RARE股价下跌1.5% MREO下跌16% 同期行业跌幅为2% [4][5]

Key Takeaways LLY stock is down 15.7% in a year due to earnings miss, guidance cut and Novo Nordisk's rising momentum. Mounjaro and Zepbound now drive 48% of LLY's revenues, fueled by global launches and improving supply. LLY expects 2025 revenues of $58B to $61B, backed by new drugs.Eli Lilly and Company’s (LLY) stock has declined 15.7% in the past year. The first-quarter earnings miss, guidance cut and some positive developments at rival Novo Nordisk (NVO) were the primary reasons for the dip. The uncer ...