UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q For the transition period from to Commission File Number 001-34899 Pacific Biosciences of California, Inc. (Exact name of registrant as specified in its charter) (State or other jurisdiction of incorporation or organization) 1305 O'Brien Drive Menlo Park, CA 94025 (Address of principal executive offices) (Zip Code) (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quar ...

Pacific Biosciences of California, Inc. (NASDAQ:PACB) Q2 2022 Earnings Conference Call August 3, 2022 5:00 PM ET Company Participants Todd Friedman – Director of Investor Relations Christian Henry – President and Chief Executive Officer Susan Kim – Chief Financial Officer Conference Call Participants Kyle Mikson – Canaccord Tejas Savant – Morgan Stanley Dan Brennan – Cowen Operator Welcome to the PacBio’s Second Quarter Fiscal Year 2022 Earnings Call. All participants will be in a listen-only mode. [Operato ...

For the quarterly period ended March 31, 2022 Or UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001-34899 Pacific Biosciences of California, Inc. (Exact name of registrant as specified in its charter) Delaware 16-1590339 (State ...

Pacific Biosciences of California, Inc. (NASDAQ:PACB) Q1 2022 Earnings Conference Call May 4, 2022 5:00 PM ET Company Participants Todd Friedman - Director, IR Christian Henry - President and Chief Executive Officer Susan Kim - Chief Financial Officer Conference Call Participants Dan Brennan - Cowan David Westenberg - Piper Sandler Tejas Savant - Morgan Stanley Kyle Mikson - Canaccord Operator Good day and welcome to the PacBio First Quarter Fiscal 2022 Financial Results Conference Call. All participants wi ...

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 Or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001-34899 Pacific Biosciences of California, Inc. (Exact name of registrant as specified in its charter) Delaware 16-1590339 (State or ot ...

| --- | --- | |-------------------------------------------|-------| | | | | 11th Annual SVB Leerink Global Healthcare | | 1 For research use only. Not for use in diagnostic procedures. © 2022 PacBio. All rights reserved. PacBio, the PacBio logo, SMRT, SMRTbell, Iso-Seq, and Sequel are trademarks of PacBio. All other trademarks are the sole property of their respective owners. Safe harbor statement All statements in this presentation (and any accompanying oral presentation) that are not historical are forwar ...

Pacific Biosciences of California, Inc. (NASDAQ:PACB) Q4 2021 Earnings Conference Call February 15, 2022 4:30 PM ET Company Participants Todd Friedman - Director, IR Christian Henry - President, CEO & Director Susan Kim - CFO Mark Van Oene - COO Conference Call Participants Kyle Mikson - Canaccord Genuity Tejas Savant - Morgan Stanley Tycho Peterson - JPMorgan Chase Daniel Brennan - Cowen and Company Ross Osborn - Cantor Fitzgerald Operator Good day, and thank you for standing by. Welcome to the Pacific Bio ...

| --- | --- | |--------------------------------------------------------------------------------------------------------------------|-------| | | | | Transforming PacBio 40th Annual J.P. Morgan Healthcare Christian Henry \| President and Chief Executive Officer | | 1 For research use only. Not for use in diagnostic procedures. © 2022 PacBio. All rights reserved. PacBio, the PacBio logo, SMRT, SMRTbell, Iso-Seq, and Sequel are trademarks of PacBio. All other trademarks are the sole property of their respectiv ...

1 STIFEL 2021 VIRTUAL HEALTHCARE CONFERENCE SUSAN KIM, CFO © 2021 PACIFIC BIOSCIENCES OF CALIFORNIA, INC. ALL RIGHTS RESERVED. PACIFIC BIOSCIENCES SAFE HARBOR STATEMENT All statements in this presentation (and any accompanying oral presentation) that are not historical are forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements generally relate to future events or ou ...

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 Or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001-34899 Pacific Biosciences of California, Inc. (Exact name of registrant as specified in its charter) Delaware 16-1590339 (St ...