The ACR-368-tailored OncoSignature assay is being used to predict patients most likely to respond to ACR-368 in Acrivon’s ongoing, registrational-intent, multicenter Phase 2b trial of ACR-368 in patients with endometrial cancer and other tumor types Clinical data presented at ESMO 2024 demonstrates statistically significant segregation of patient responders in biomarker-positive versus biomarker-negative subgroups based on prospective OncoSignature patient selection (p-value = 0.009) Drug-tailored, propriet ...

Fort Lauderdale, FL, Feb. 05, 2025 (GLOBE NEWSWIRE) -- Algorhythm Holdings, Inc. (“Algorhythm” or “Company”) (NASDAQ: RIME) – an AI technology and consumer electronics holding company, announced today the date of effectiveness and the ratio of a forthcoming reverse stock split (the “Reverse Split”) of the Company’s Common Stock (the “Common Stock”). On January 13, 2025, the Company announced, on a Current Report on Form 8-K, the voting results from the annual meeting of stockholders (the “Meeting”) held tha ...

MILWAUKEE, Feb. 05, 2025 (GLOBE NEWSWIRE) -- Twin Disc, Inc. (NASDAQ: TWIN) today reported results for the second quarter ended December 27, 2024. Fiscal Second Quarter 2025 Highlights Sales increased 23.2% year-over-year to $89.9 million, organic sales* increased 10.1%Net income attributable to Twin Disc was $0.9 millionEBITDA* increased 13.5% year-over-year to $6.3 millionOperating cash flow of $4.3MHealthy six-month backlog of $124.0 million supported by strong ongoing order activity CEO Perspective “Thi ...

SINGAPORE, Feb. 05, 2025 (GLOBE NEWSWIRE) -- Uni-Fuels Holdings Limited (NASDAQ: UFG), (“Uni-Fuels” or the “Company”), a global provider of marine fuel solutions headquartered in Singapore, today announced its bronze sponsorship of the International Bunker Industry Association (IBIA) Annual Dinner 2025 to take place on February 24 at the Grosvenor House Hotel in Mayfair, London. The annual event, which brings together key stakeholders, industry leaders, and decision makers from across the maritime and marin ...

SAN DIEGO, Feb. 05, 2025 (GLOBE NEWSWIRE) -- Ventyx Biosciences, Inc. (Nasdaq: VTYX) (“Ventyx”, “Company”), a clinical-stage biopharmaceutical company focused on developing innovative oral therapies for patients with autoimmune, inflammatory, and neurodegenerative diseases, today announced that Company executives will participate in the upcoming Oppenheimer 35th Annual Healthcare Life Sciences Conference. Event: Oppenheimer 35th Annual Healthcare Life Sciences ConferenceLocation: VirtualDate: Wednesday, Feb ...

PHOENIX, Feb. 05, 2025 (GLOBE NEWSWIRE) -- WillScot Holdings Corporation (“WillScot” or the “Company”) (Nasdaq: WSC), a leader in innovative temporary flexible space solutions, today announced that it will release its fourth quarter 2024 financial results on February 20, 2025, after market close. The Company’s management team will host a conference call and webcast on February 20, 2025, at 5:30 p.m. EST to discuss the Company’s results. To access the live call by phone, use the following link by clicking he ...

DOYLESTOWN, Pa., Feb. 05, 2025 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (NASDAQ:APRE) ("Aprea", or the "Company"), a clinical-stage biopharmaceutical company developing innovative treatments that exploit specific cancer cell vulnerabilities while minimizing damage to healthy cells, today provided an update on its existing patent portfolio. "Our strong patent portfolio reflects our commitment to innovation and leadership in the field of DNA Damage Response therapeutics," said Oren Gilad, Ph.D., President ...

Rapid menu expansion with new high-plex human and mouse neurobiology panels joining the recently launched Human IO60 and Mouse FFPE IO Panels The new offerings solidify leadership in spatial biology and broaden reach to new verticals MARLBOROUGH, Mass., Feb. 05, 2025 (GLOBE NEWSWIRE) -- Akoya Biosciences, a spatial proteomics leader, announced its reagent product roadmap today, featuring new ultrahigh-plex neurobiology panels for human and mouse applications. Building on the success of the Human IO60 and Mo ...

PRINCETON, N.J., Feb. 05, 2025 (GLOBE NEWSWIRE) -- PDS Biotechnology Corporation (NASDAQ:PDSB) ("PDS Biotech" or the "Company"), a late-stage immunotherapy company focused on transforming how the immune system targets and kills cancers, today reaffirmed the Company's guidance of initiating its VERSATILE-003 Phase 3 clinical trial of Versamune® HPV plus pembrolizumab for first-line treatment of recurrent and/or metastatic (R/M) HPV16-positive head and neck squamous cell cancer (HNSCC) in the first quarter of ...

文章核心观点 临床阶段生物技术公司Indaptus Therapeutics获加拿大卫生部临床试验授权，将其美国进行中的INDP - D101临床试验扩展至加拿大站点，还计划提交修正案纳入与百济神州PD - 1抑制剂的联合试验，有望加速收集临床数据，推动癌症治疗进展 [1] 公司动态 - 公司获加拿大卫生部临床试验授权，可将进行中的美国临床试验INDP - D101扩展至加拿大站点，按当前方案招募患者，还计划提交修正案纳入与百济神州PD - 1抑制剂tislelizumab的联合试验 [1] - 公司CEO称将加拿大研究人员和患者纳入临床工作可创建更多样、强大的数据集，首席医学官表示增加加拿大试验点能加速收集有价值临床数据，增强试验基础设施以加速了解Decoy20治疗潜力、优化给药方案和改善治疗结果 [2] 公司介绍 - 公司基于免疫疗法一个多世纪的进展发展而来，其创新方法基于多靶点激活免疫系统信号假设，专利技术由减毒和灭活的非致病性革兰氏阴性细菌单菌株组成，产生多激动剂Decoy平台 [3] - 公司候选产品设计为降低静脉毒性，保留激活先天和适应性免疫细胞及途径能力，在临床前模型中对多种癌症和病毒感染有单药或联合治疗活性，还能产生免疫记忆并使肿瘤炎症特征从“冷”转“热” [3] - 临床前非临床毒理学研究显示静脉给药不会持续诱导细胞因子释放综合征标志性生物标志物，可能因靶向肝脏、脾脏和肿瘤并快速清除候选产品 [3]