NEW YORK, April 28, 2025 (GLOBE NEWSWIRE) -- The Gross Law Firm issues the following notice to shareholders of Actinium Pharmaceuticals, Inc. (NYSE: ATNM). Shareholders who purchased shares of ATNM during the class period listed are encouraged to contact the firm regarding possible lead plaintiff appointment. Appointment as lead plaintiff is not required to partake in any recovery. CONTACT US HERE: https://securitiesclasslaw.com/securities/actinium-loss-submission-form/?id=145068&from=3 CLASS PERIOD: Octobe ...

核心观点 - ATNM-400在治疗前列腺癌模型中显示出比Pluvicto更高的疗效，单次40 µCi/kg剂量可实现99.8%的肿瘤生长抑制[1][6] - ATNM-400靶向非PSMA受体，该受体在转移性去势抵抗性前列腺癌(mCRPC)中高表达且不受Pluvicto治疗影响[4][6] - ATNM-400在Pluvicto治疗失败后仍能持续抑制肿瘤生长，展现对耐药模型的强效抗肿瘤活性[3][6] 药物特性 - ATNM-400采用Ac-225放射性同位素，比Pluvicto的Lu-177更具效力，能通过双链DNA断裂实现不可逆细胞杀伤[4][10] - 生物分布分析显示ATNM-400在肿瘤中持续摄取至216小时，48小时内从血液中快速清除且对关键器官无毒性[10] - 两种剂量水平下均表现良好耐受性，无显著毒性反应[1][10] 临床前数据 - 在22Rv1前列腺癌模型中，ATNM-400比Pluvicto显著减少肿瘤体积(p < 0.0001)[2][5] - 对Pluvicto耐药肿瘤模型仍显示强劲抗肿瘤活性和生长抑制[3][6] - 单剂量40 µCi/kg实现近100%肿瘤生长抑制，支持其作为替代方案的潜力[1][6] 市场与竞争 - Pluvicto(诺华销售)2024年销售额达13.9亿美元，ATNM-400作为非PSMA靶向疗法具备差异化优势[1][4] - Ac-225同位素具有更短路径长度，可能减少脱靶效应，增强治疗精准度[4] - 公司拥有230项专利，涵盖Ac-225同位素生产等关键技术[8] 研发管线 - 除ATNM-400外，公司主要候选药物Actimab-A针对AML，已展示与CLAG-M联用的高完全缓解率[8] - 与NCI合作开展Actimab-A三联疗法(联合Venetoclax和ASTX-727)的临床试验[8] - 开发Iomab-ACT作为下一代细胞基因疗法预处理方案[8]

NEW YORK, April 28, 2025 /PRNewswire/ -- The Gross Law Firm issues the following notice to shareholders of Actinium Pharmaceuticals, Inc. (NYSE: ATNM).Shareholders who purchased shares of ATNM during the class period listed are encouraged to contact the firm regarding possible lead plaintiff appointment. Appointment as lead plaintiff is not required to partake in any recovery.CONTACT US HERE:https://securitiesclasslaw.com/securities/actinium-loss-submission-form/?id=145056&from=4CLASS PERIOD: October 31, 20 ...

Faruqi & Faruqi, LLP Securities Litigation Partner James (Josh) Wilson Encourages Investors Who Suffered Losses In Actinium To Contact Him Directly To Discuss Their Options If you purchased or acquired securities in Actinium between October 31, 2022 and August 2, 2024 and would like to discuss your legal rights, call Faruqi & Faruqi partner Josh Wilson directly at 877-247-4292 or 212-983-9330 (Ext. 1310). [You may also click here for additional information] NEW YORK, April 26, 2025 (GLOBE NEWSWIRE) -- Faru ...

NEW YORK, April 25, 2025 /PRNewswire/ -- Levi & Korsinsky, LLP notifies investors in Actinium Pharmaceuticals, Inc. ("Actinium" or the "Company") (NYSE: ATNM) of a class action securities lawsuit.CLASS DEFINITION: The lawsuit seeks to recover losses on behalf of Actinium investors who were adversely affected by alleged securities fraud between October 31, 2022 and August 2, 2024. Follow the link below to get more information and be contacted by a member of our team:https://zlk.com/pslra-1/actinium-lawsuit-s ...

NEW YORK, April 23, 2025 (GLOBE NEWSWIRE) -- The Gross Law Firm issues the following notice to shareholders of Actinium Pharmaceuticals, Inc. (NYSE: ATNM). Shareholders who purchased shares of ATNM during the class period listed are encouraged to contact the firm regarding possible lead plaintiff appointment. Appointment as lead plaintiff is not required to partake in any recovery. CONTACT US HERE: https://securitiesclasslaw.com/securities/actinium-loss-submission-form/?id=144420&from=3 CLASS PERIOD: Octobe ...

NEW YORK  , April 22, 2025 /PRNewswire/ -- Levi & Korsinsky, LLP notifies investors in Actinium Pharmaceuticals, Inc. ("Actinium" or the "Company") (NYSE: ATNM) of a class action securities lawsuit.CLASS DEFINITION: The lawsuit seeks to recover losses on behalf of Actinium investors who were adversely affected by alleged securities fraud between October 31, 2022 and August 2, 2024. Follow the link below to get more information and be contacted by a member of our team:https://zlk.com/pslra-1/actinium-lawsuit ...

NEW YORK, April 21, 2025 (GLOBE NEWSWIRE) -- Levi & Korsinsky, LLP notifies investors in Actinium Pharmaceuticals, Inc. ("Actinium" or the "Company") (NYSE: ATNM) of a class action securities lawsuit. CLASS DEFINITION: The lawsuit seeks to recover losses on behalf of Actinium investors who were adversely affected by alleged securities fraud between October 31, 2022 and August 2, 2024. Follow the link below to get more information and be contacted by a member of our team: https://zlk.com/pslra-1/actinium-law ...

NEW YORK, April 21, 2025 /PRNewswire/ -- The Gross Law Firm issues the following notice to shareholders of Actinium Pharmaceuticals, Inc. (NYSE: ATNM).Shareholders who purchased shares of ATNM during the class period listed are encouraged to contact the firm regarding possible lead plaintiff appointment. Appointment as lead plaintiff is not required to partake in any recovery.CONTACT US HERE:https://securitiesclasslaw.com/securities/actinium-loss-submission-form/?id=143830&from=4 CLASS PERIOD: October 31, 2 ...

NEW YORK, April 18, 2025 (GLOBE NEWSWIRE) -- The law firm of Kirby McInerney LLP reminds investors that a class action lawsuit has been filed in the U.S. District Court for the Southern District of New York on behalf of those who acquired Actinium Pharmaceuticals, Inc. (“Actinium” or the “Company”) (NYSE:ATNM) securities during the period from October 31, 2022, through August 2, 2024 (“the Class Period”). Investors have until May 27, 2025, to apply to the Court to be appointed as lead plaintiff in the lawsu ...