– On track for first FDA Biologics License Application (BLA) approved cell therapy in orphan indication relapsed/refractory AL Amyloidosis – Los Angeles, CA, Sept. 18, 2025 (GLOBE NEWSWIRE) -- Immix Biopharma, Inc. (“ImmixBio”, “Company”, “We” or “Us” or ”IMMX”), a clinical-stage biopharmaceutical company developing cell therapies for AL Amyloidosis and other serious diseases, today announced that 50% enrollment milestone has already been surpassed in NEXICART-2, its relapsed/refractory AL Amyloidosis clini ...

收购交易核心条款 - 罗氏以35亿美元收购89bio 交易预计2025年第四季度完成 [1][2] - 收购对价包含每股14.5美元现金 股权价值约24亿美元 另附最高每股6美元的或有价值权 [3][4] - 若全部里程碑达成 89bio股东将额外获得约10亿美元现金 总溢价达60日均价的52% [4][5] 标的资产技术价值 - 核心资产pegozafermin为FGF21类似物 针对F2-F4阶段MASH患者开展三期临床 [2][6] - 该药物采用独特作用机制 具备与肠促胰岛素药物联合开发的协同潜力 [6] - MASH作为肥胖常见并发症 有望为罗氏带来重大收入机会 [7] 战略布局深化 - 此次收购强化罗氏在心血管、肾脏及代谢疾病领域的产品组合 [1][6] - 公司近期通过收购Carmot Therapeutics获得三个肥胖/糖尿病临床阶段资产 [10] - 与Zealand Pharma合作开发减肥药物petrelintide 进一步拓展肥胖治疗领域 [9] 行业并购趋势 - 2025年医药行业并购活动显著加速 打破2024年低迷态势 [10] - 诺华制药14亿美元收购Tourmaline Bio 获得心血管三期候选药物pacibekitug [11] - 诺华6月以8亿美元收购Regulus Therapeutics 葛兰素史克7月收购efimosfermin alfa拓展肝病管线 [12][13]

Alkermes (NASDAQ:ALKS) is one of the best beginner stocks to buy, according to analysts. On September 9, HC Wainwright reiterated a ‘Neutral’ rating on the stock and a $46 price target. The stance follows the company’s positive results from the Vibrance-1 phase 2 study. HC Wainwright Affirms Alkermes (ALKS) ‘Neutral’ Rating on Vibrance-1 Phase 2 Study Study results show that Alixorexton is the first orexin 2 receptor agonist to demonstrate a clinically meaningful and statistically significant impact on w ...

On Thursday, Roche Holdings AG RHHBY agreed to acquire 89bio, Inc. ETNB for $2.4 billion. 89Bio is a clinical-stage biopharmaceutical company focused on the development and commercialization of therapies for liver and cardiometabolic diseases.Roche will acquire the company for $14.50 per share, representing a premium of approximately 79% to 89bio’s closing stock price on September 17, 2025, the last trading day before the announcement of the transaction, and a premium of 52% to 89bio’s 60-day volume-weighte ...

AbbVie Inc. (NYSE:ABBV) is among the high growth mega cap stocks you can buy and hold for the next 3 years. Evan Seigerman, an analyst at BMO Capital, increased the price target on AbbVie Inc. (NYSE:ABBV) to $240 from $215 with an ‘Outperform’ rating. This potential upside of nearly 10% follows the company’s announcement that it has resolved litigation with generic drugmakers, allowing for the early market entry of generic Rinvoq. Many believe that generic competition market entry won’t occur until 2037, ...

公司业务与行业定位 - Sutro Biopharma是一家专注于开发癌症疗法的生物技术公司 使用专有平台开发生物制剂和抗体药物偶联物[1] - 公司在竞争格局中面临多家同业公司 包括Scholar Rock Holding Corporation、Replimune Group、Y-mAbs Therapeutics、Crinetics Pharmaceuticals和Kezar Life Sciences 这些公司均致力于创新疗法开发[1] 财务绩效分析 - Sutro Biopharma的投入资本回报率为-105.71% 显著低于其43.22%的加权平均资本成本 导致ROIC与WACC比率为-2.45 表明公司未能产生覆盖资本成本的回报[2] - 同业公司Scholar Rock Holding Corporation的ROIC为-109.48% WACC为5.32% ROIC与WACC比率达-20.57 显示其资本覆盖能力较Sutro更弱[3] - Replimune Group和Kezar Life Sciences分别呈现-10.70和-10.94的ROIC与WACC比率 表明存在显著负利差[3] 同业比较表现 - Y-mAbs Therapeutics的ROIC为-27.64% WACC为6.11% ROIC与WACC比率为-4.53 在同行中相对更接近盈亏平衡点[4] - Crinetics Pharmaceuticals的ROIC与WACC比率为-6.99 虽然仍为负值 但财务表现优于部分同业公司[4] - 尽管所有同业公司目前回报均低于资本成本 但Sutro的ROIC与WACC比率相对优于部分同行 显示其资本效率处于相对较好位置[5][6]

核心观点 - 公司被列为2025年迄今13只超卖医疗股之一 股价面临波动性 [1][4] - 公司核心药物ivonescimab在中国获批并展示积极临床数据 但北美及欧洲试验结果存在差异 [2][3][4] 临床进展 - 核心药物ivonescimab针对EGFR突变非小细胞肺癌的HARMONi III期试验显示 联合铂类化疗组无进展生存期较安慰剂组有统计学显著改善 [2] - 总生存期呈积极趋势但未达统计学显著性 [2] - 中国已批准ivonescimab作为PD-L1阳性晚期非小细胞肺癌的一线治疗药物 [3] - 全球III期试验患者招募持续进行 包括新启动的美国队列 [3] 商业与监管动态 - 地理扩张体现于中国市场获批 [3] - 面临与Pinnacle研究相关的证券欺诈诉讼法律审查 [4] 市场表现 - 2025年股价波动源于投资者对北美欧洲与中国试验结果差异的担忧 影响商业潜力预期 [4]

Wugen closed a $115 million equity financing led by Fidelity Management & Research Company HCW Biologics holds a minority equity interest in Wugen MIRAMAR, Fla., Sept. 18, 2025 (GLOBE NEWSWIRE) -- HCW Biologics Inc. (the “Company” or “HCW Biologics”), (NASDAQ: HCWB), a U.S.-based clinical-stage biopharmaceutical company focused on discovering and developing novel immunotherapies to lengthen healthspan by disrupting the link between inflammation and age-related diseases, congratulates Wugen, Inc. (“Wugen”) o ...

公司业务与战略 - 公司是一家临床阶段生物制药公司 专注于开发肿瘤学和免疫疗法产品[4] - 公司使命是通过创新的后期治疗候选药物 解决高度未满足需求的癌症和罕见儿科适应症[4] - 公司通过合资企业进行药物许可和共同开发 目前拥有GMP Bio合资企业45%的股权[4] 技术优势与知识产权 - 公司应用人工智能、纳米医学和创新临床方法重新定义生物技术[3] - 拥有强大的知识产权组合 包括约500项专利申请和75项授权专利[3] - CEO个人拥有150多项专利申请和39项美国授权专利 进一步强化公司技术储备[4] 研发重点领域 - 专注于RNA药物、免疫疗法和靶向治疗领域的进展[2] - 重点攻克胶质母细胞瘤和胰腺癌等最难治疗的致命癌症[2] - 同时关注罕见儿科疾病治疗领域 致力于减少对年轻患者的伤害[2] 行业地位与认可 - 公司因在重大未满足医疗需求领域的突出表现获得专业媒体报道[1][3] - 通过NetworkNewsWire金融新闻平台向投资界传播公司进展[1][5] - 报道强调公司在癌症研究领域的突破为全球患者带来新希望[2]

Grant of First Method of Use Patent Adds New Pillar to Grace’s Multi-layered Intellectual Property and Potential Market Exclusivity Protection Patent Coverage Extended to 2043 PRINCETON, N.J., Sept. 18, 2025 (GLOBE NEWSWIRE) -- Grace Therapeutics, Inc. (Nasdaq: GRCE) (Grace Therapeutics or the Company), a late-stage, biopharma company advancing GTx-104, a clinical-stage, novel, injectable formulation of nimodipine being developed for I.V. infusion to address significant unmet medical needs in aSAH patients, ...