-          First participants with obesity or overweight with at least one weight-related comorbidity have been dosed in a U.S. 12-week Phase IIa study with once-monthly subcutaneous (SQ) depot formulation of small molecule GLP-1 receptor agonist ASC30. -          Ultra-long-acting SQ depot formulation of small molecule ASC30 demonstrated a 36-day half-life in participants with obesity in the Phase Ib study, supporting once monthly administration. -          Phase Ib study also demonstrated that compared to ...

诉讼事件 - 针对Replimune Group Inc的集体诉讼已提交 指控公司及其部分高管可能涉及证券欺诈或其他非法商业行为 [1][2] - 诉讼与FDA拒绝批准RP1联合nivolumab治疗晚期黑色素瘤的BLA申请直接相关 [3] FDA监管决定 - FDA发布完全回应函(CRL) 拒绝批准RP1的BLA申请 认为现有数据不足以证明疗效 [3] - IGNYTE临床试验被FDA认为设计不足 患者群体异质性导致结果难以解释 [3] - 需要解决确认性试验设计相关问题 包括成分贡献度分析 但未提出安全性问题 [3] 市场反应 - 公司股价在FDA决定公布当日暴跌9 52美元 跌幅达77 24% 收盘价2 81美元 [3] 法律程序 - 投资者可在2025年9月22日前申请成为首席原告 需提供持股证明和联系方式 [1][3] - Pomerantz律所专门处理证券集体诉讼 在多个国家设有办事处 [4]

NEW YORK, July 27, 2025 (GLOBE NEWSWIRE) -- WHY: Rosen Law Firm, a global investor rights law firm, announces the filing of a class action lawsuit on behalf of purchasers of common stock of Alto Neuroscience, Inc. (NYSE: ANRO): (i) pursuant and/or traceable to Alto’s initial public offering conducted on or about February 2, 2024 (the “IPO”); and/or (ii) securities between February 2, 2024 and October 22, 2024, both dates inclusive (the “Class Period”). If you wish to serve as lead plaintiff, you must move ...

磁纳米微萃取技术可以减少有害有机溶剂的使用，简化了繁琐的样品洗脱步骤，易于实现自动化，并且 可以对样品中的痕量化合物进行高倍的富集。另一方面，由于固相萃取过程的扩散和传质速率有限，因 此萃取过程的平衡时间通常较长。M-SPE与传统的SPE技术不同，这种微纳米颗粒可以完全暴露于待测 体系，并与之充分接触，因此能够在短时间内从大体积的待测体系中吸附和萃取待测物质。此外磁性颗 粒可以很容易地通过外加磁场从待测体系中分离和收集，避免了繁琐的过滤或离心过程。 二、技术背景 经过多年发展，我国磁性固相萃取技术取得重大进展，据专利之星数据显示，2024年我国磁性固相萃取 相关专利申请数量突破25件，这是近十年来继2022年再次达到最高峰值，而从专业申请省份来看，我国 磁性固相萃取相关专利申请数量主要集中在江苏省、浙江省、上海市、广东省、北京市等地，占比超 60%。从专利申请企业来看，我国磁性固相萃取相关专利申请量前三甲企业为天津国科医工科技发展有 限公司、杭州凯莱谱质造科技有限公司和上海睿质科技有限公司。 内容概要：与传统固相萃取技术，磁性固相萃取技术在处理效率、自动化、运行成本、实验数据稳定性 等方面具有明显优势，近年来 ...

美国退休储蓄现状 - 截至2022年美国家庭退休储蓄中位数仅为87,000美元，半数家庭储蓄低于此水平 [1] - 即使储蓄金额高于中位数，仍可能不足以支撑舒适退休生活 [1] 投资策略建议 - 增加收入储蓄比例仅是基础，需通过优化投资组合实现更高收益 [2] - 推荐长期持有具备增长潜力的股票以加速资产增值 [3] Recursion Pharmaceuticals - 公司开发AI驱动的药物研发平台Recursion OS，利用3,600万GB生物化学数据将传统耗时数年的药物测试缩短至数天 [5] - 技术已商业化，罗氏/赛诺菲等药企采用其平台，同时公司推进自主药物研发 [6] - 行业前景：Straits Research预测至2030年AI药物开发行业年复合增长率达32% [8] - 当前仍处亏损阶段，但接近盈利转折点，2021年峰值后股价持续低迷或现买入机会 [7][8] Shopify - 2023年平台促成2,923亿美元商品交易（同比+24%），营收89亿美元中净利润超10亿美元 [11] - 全球仅约20%零售发生在线上，实体店转型电商将带来持续增长空间 [13] - 分析师预计未来三年年营收增速维持在20%左右，品牌自建电商趋势强化公司优势 [14] Nio - 2023年Q2交付72,056辆电动车（同比+26%），主要市场为中国但正拓展欧洲 [16] - 中国电动车市场持续扩张：上月销量110万辆（占汽车总销量超50%），同比增速25% [17] - 国际能源署预测2030年中国电动车渗透率将达80%，政策驱动下欧洲市场同步增长 [19] - 当前尚未盈利但生产/盈利指标持续改善，规模化后有望实现收支平衡 [20]

NEW YORK, July 26, 2025 (GLOBE NEWSWIRE) -- WHY: Rosen Law Firm, a global investor rights law firm, continues to investigate potential securities claims on behalf of shareholders of GeneDx Holdings Corp. (NASDAQ: WGS) resulting from allegations that GeneDx may have issued materially misleading business information to the investing public. SO WHAT: If you purchased GeneDx securities you may be entitled to compensation without payment of any out of pocket fees or costs through a contingency fee arrangement. ...

SAN DIEGO, July 26, 2025 (GLOBE NEWSWIRE) -- The law firm of Robbins Geller Rudman & Dowd LLP announces that the Rocket Pharmaceuticals class action lawsuit – captioned Ho v. Rocket Pharmaceuticals, Inc., No. 25-cv-10049, and pending in the District of New Jersey – seeks to represent purchasers or acquirers of Rocket Pharmaceuticals, Inc. (NASDAQ: RCKT) securities and charges Rocket Pharmaceuticals as well as one of Rocket Pharmaceuticals’ executives with violations of the Securities Exchange Act of 1934. A ...

Sona Nanotech Inc (CSE:SONA, OTCQB:SNANF) CEO David Regan talked with Proactive about the company’s recent ethics committee approval for a pilot cancer study. This approval represents the next step in Sona Nanotech's clinical development pathway, building on its current early feasibility study focused on late-stage melanoma patients. The early study, which is currently underway, involves 10 patients with late-stage melanoma for whom other treatments have failed. Results from this group are expected within t ...

My name is Myriam Hernandez Alvarez. I received the Electronics and Telecommunication Engineering degree from the Escuela Politecnica Nacional, Quito, Ecuador, the M.Sc. degree in computer science from Ohio University, Athens, OH, USA, a graduate degree in Business Management from Universidad Andina Simon Bolivar, Quito, Ecuador, and the Ph.D. degree in computer applications from the University of Alicante, Spain.Disclosure: I collaborate professionally with Edgar Torres H, who is also an author on Seeking ...

NEW YORK, July 26, 2025 (GLOBE NEWSWIRE) -- Leading securities law firm Bleichmar Fonti & Auld LLP announces that a lawsuit has been filed against Replimune Group, Inc. (NASDAQ: REPL) and certain of the Company’s senior executives for potential violations of the federal securities laws. If you invested in Replimune, you are encouraged to obtain additional information by visiting: https://www.bfalaw.com/cases/replimune-group-class-action-lawsuit. Investors have until September 22, 2025, to ask the Court to b ...