Global ingredient supplier Corbion has once again demonstrated its strong commitment to sustainability, earning high marks in climate, water, and supplier engagement in CDP’s Disclosure Cycle 2024. Corbion, the sustainable ingredients company dedicated to preserving what matters, earned scores of A- in Climate, B in Water, and A- in Supplier Engagement, as determined by CDP, a global non-profit that runs the world’s only independent environmental disclosure system. Results are based on data reported by Corb ...

文章核心观点 - 欧洲委员会批准Itovebi与palbociclib和fulvestrant联用治疗特定乳腺癌 该批准基于INAVO120试验数据 显示该方案可显著提高无进展生存期和总生存期 [1][2] 药物相关信息 - Itovebi是口服靶向治疗药物 可对特定乳腺癌患者提供耐受性良好且持久的疾病控制 其设计旨在减少治疗负担和毒性 与其他PI3K抑制剂不同 [5] - Itovebi除获欧洲委员会批准外 还在美国、瑞士等多地获批治疗特定乳腺癌 相关数据正在接受其他全球卫生当局审查 [6] 临床试验相关 INAVO120研究 - 该研究是一项III期、随机、双盲、安慰剂对照研究 评估Itovebi与palbociclib和fulvestrant联用的疗效和安全性 研究对象为特定乳腺癌患者 [7] - 研究包括325名患者 随机分配到研究组或对照组 主要终点是无进展生存期 次要终点包括总生存期、客观缓解率和临床获益率 [9] - 研究结果显示 Itovebi方案使疾病恶化或死亡风险降低57% 无进展生存期达15.0个月 而单独使用palbociclib和fulvestrant为7.3个月 [2] - INAVO120最终总生存期分析显示 Itovebi方案使死亡风险降低33% 与单独使用palbociclib和fulvestrant相比 该治疗方案将化疗时间推迟约两年 [3] 其他研究 - Itovebi目前正在三项公司赞助的III期研究（INAVO121、INAVO122、INAVO123）中进行研究 均针对PIK3CA突变的局部晚期或转移性乳腺癌 采用不同的联合治疗方案 [4][17] 乳腺癌相关信息 - ER阳性是HR阳性乳腺癌的一种亚型 约占所有乳腺癌病例的70% 其肿瘤细胞有雌激素受体 可促进肿瘤生长 [10] - 约40%的ER阳性乳腺癌有PIK3CA突变 预后较差 此次批准有助于满足这一紧迫的未满足需求 [8] - 被诊断为ER阳性和HR阳性转移性乳腺癌的患者常面临疾病进展和治疗副作用风险 需要更多治疗选择 PI3K信号通路在HR阳性乳腺癌中常失调 [11] 公司相关信息 - 罗氏成立于1896年 是全球最大的生物技术公司和体外诊断领域的全球领导者 致力于乳腺癌研究超30年 [12][13] - 可持续发展是罗氏业务的组成部分 公司致力于到2045年实现净零排放 旗下Genentech是其在美国的全资子公司 并持有日本中外制药的多数股权 [14]

HIAB CORPORATION, HALF-YEAR FINANCIAL REPORT JANUARY–JUNE 2025, 23 JULY 2025 AT 8:00 AM (EEST) Hiab's half-year financial report January–June 2025: Strong performance in the first half Key takeaways from the quarter Orders received in Q2 increased from the comparison period to EUR 377 (348) millionComparable operating profit margin in Q2 improved to 15.0 (14.5) percent due to strong execution on commercial and supply chain actionsElevated market uncertainty due to the increased trade tensions continuedOutlo ...

Equinor (OSE: EQNR, NYSE: EQNR) will on 24 July 2025 commence the third tranche of up to USD 1,265 million of the share buy-back programme for 2025, as announced in relation with the second quarter results 23 July 2025. In this third tranche of the share buy-back programme for 2025, shares for up to USD 417.5 million will be purchased in the market, implying a total third tranche of up to USD 1,265 million including shares to be redeemed from the Norwegian State. The tranche will end no later than 27 Octob ...

Key information relating to the cash dividend to be paid by Equinor (OSE: EQNR, NYSE: EQNR) for the second quarter 2025. Cash dividend amount: 0.37 Announced currency: USD Last day including rights: 12 November 2025 Ex-date Oslo Børs: 13 November 2025 Ex-date New York Stock Exchange: 14 November 2025 Record date: 14 November 2025 Payment date: 26 November 2025 Date of approval: 22 July 2025 Other information: The cash dividend per share in NOK will be communicated on 20 November 2025. This information is p ...

Equinor (OSE:EQNR, NYSE:EQNR) delivered an adjusted operating income* of USD 6.53 billion and USD 1.74 billion after tax* in the second quarter of 2025. Equinor reported a net operating income of USD 5.72 billion and a net income of USD 1.32 billion. Adjusted net income* was USD 1.67 billion, leading to adjusted earnings per share* of USD 0.64. Solid financial results Strong operational performance and production growthHigher US onshore gas production capturing higher pricesStable cost and capex in line wit ...

具体来讲， 作为人工智能在出行行业的最大应用场景之一， Robotaxi已成为出行服务领域高确定 性趋势。 如祺出行在Robotaxi界的发展模式类似全球出行公司Uber。 本文为IPO早知道原创 作者｜ Stone Jin 微信公众号｜ipozaozhidao 据 IPO早知道消息， 如祺出行 于 7月23日 宣布正式启动 "Robotaxi+"战略。 如祺出行称计划凭借平台的资源聚合优势和运营服务经验，面向地方监管机构、自动驾驶技术公司及 其他生态合作方提供一揽子解决方案，以共同加速 Robotaxi大规模商业化落地。 某种程度上而言， 如祺出行在 Robotaxi界的发展模式如同全球出行公司Uber，两者均正在迅速拓 展 Robotaxi 领 域 的 合 作 伙 伴 ， 并 有 望 通 过 发 挥 作 为 出 行 公 司 在 运 营 方 面 的 优 势 、 逐 步 做 强 为 Robotaxi规模化进行服务的能力。 今年上半年以来 ， 受 Robotaxi的持续进展带动，Uber股价已 累涨达55%。 "出行服务的未来必然是Robotaxi。"如祺出行CEO蒋华在发布会上表示，Robotaxi赛道已经进 ...

PayPal announced Wednesday it has partnered with global wallet companies to create a platform called PayPal World that is designed to make cross-border commerce easier. The platform will allow users to pay others using their local wallets and payment systems.The company said the launch partners include India’s NPCI International Payments Limited, which operates mobile payments framework UPI (Unified Payment Interface), China’s Tenpay Global (Tencent’s Payment arm), which operates Weixin (WeChat) payment eco ...

For consumers: your domestic wallet accepted at millions more businesses around the worldFor much of the world's population, international shopping and money transfers are not just difficult, at times they are impossible. While digital wallets and payments have become the preferred payment method in many markets domestically, consumers still require an international payment method to shop overseas. Sending money across borders can be similarly frustrating, with consumers facing fees, barriers, and delays. W ...

Financial analyst by day and a seasoned investor by passion, I've been involved in the world of investing for over 15 years and honed my skills in analyzing lucrative opportunities within the market.I specialize in uncovering high quality dividend stocks and other assets that offer potential for long term-growth that pack a serious punch for bill-paying potential. I use myself as an example that with a solid base of classic dividend growth stocks, sprinkling in some Business Development Companies, REITs, an ...