分组1 - 公司设立了一个新的战略和R&D策略,以疾病为中心,利用不同的技术手段来转化或治愈目标疾病 [8][10][11] - 公司在囊性纤维化领域持续创新,先后推出了KALYDECO、ORKAMBI、SYMDEKO、TRIKAFTA等一系列CFTR调节剂,并计划推出更有效的vanzacaftor [12][13][19][20][22] - 公司还开发了首个获批的CRISPR/Cas9基因编辑疗法CASGEVY,目前正在推进产品的全球商业化 [14][16][24][26] 分组2 - 公司正在开发一种非阿片类的急性疼痛新药Suzetrigine,旨在提供有效的止痛效果但不存在成瘾风险 [27][28][31][32] - 公司在1型糖尿病领域有三个中期临床项目,分别采用移植未经编辑的胚胎干细胞源性胰岛细胞、经过免疫隐藏编辑的胰岛细胞以及使用封装装置的胰岛细胞 [33][34][35][36] - 公司通过收购Alpine Immune Sciences公司获得了一款III期准备就绪的IgA肾病候选药物Povetacicept,这与公司的战略和管线发展方向高度吻合 [38][39][40][41] 问答环节重要的提问和回答 问题1 **Myles Minter 提问** 公司在囊性纤维化领域的收入增长主要来自于哪些方面 [49][50][51] **Reshma Kewalramani 回答** 公司将通过进一步拓展更低年龄段患者群体、推出更有效的vanzacaftor以及开发mRNA疗法等方式来推动囊性纤维化业务的持续增长 问题2 **Sami Corwin 提问** CASGEVY作为一种转化性治疗,其复杂的治疗过程是否会导致收入确认存在季节性 [55][56] **Reshma Kewalramani 回答** 公司将定期报告ATC激活和患者启动治疗的进度,但不会在中间时期提供更多细节。收入确认将在患者接受输注时确认,目前尚不清楚季节性因素对此的影响

It has been about a month since the last earnings report for Vertex Pharmaceuticals (VRTX) . Shares have added about 15.8% in that time frame, outperforming the S&P 500. Will the recent positive trend continue leading up to its next earnings release, or is Vertex due for a pullback? Before we dive into how investors and analysts have reacted as of late, let's take a quick look at its most recent earnings report in order to get a better handle on the important drivers. Q1 Earnings Beat, Trikafta Drives Sales ...

It doesn't matter your age or experience: taking full advantage of the stock market and investing with confidence are common goals for all investors. Luckily, Zacks Premium offers several different ways to do both. The research service features daily updates of the Zacks Rank and Zacks Industry Rank, full access to the Zacks #1 Rank List, Equity Research reports, and Premium stock screens, all of which will help you become a smarter, more confident investor. Zacks Premium also includes the Zacks Style Score ...

Earnings Estimate Revisions Rather than focusing on anything else, we at Zacks prioritize evaluating the change in a company's earnings projection. This is because we believe the fair value for its stock is determined by the present value of its future stream of earnings. Vertex Pharmaceuticals (VRTX) has been one of the most searched-for stocks on Zacks.com lately. So, you might want to look at some of the facts that could shape the stock's performance in the near term. Over the past month, shares of this ...

Vertex Pharmaceuticals Incorporated (VRTX) has been benefiting from strong revenue growth, regulatory approvals and commercial launches in the past year. Vertex enjoys a dominant position in the cystic fibrosis (CF) market. Vertex's CF sales continue to grow, driven by its triple therapy, Trikafta (marketed as Kaftrio in Europe). In the United States, Trikafta sales are being fueled by label expansions to younger age groups (two to five years old). In the ex-U.S. markets, the drug continues to witness stron ...

Vertex Pharmaceuticals (NDAQ: VRTX) stands today as a top 20 pharma company with over a $100 billion market cap. But this biotech beacon has ridden a bumpy path to its current perch and, along the way, just may have authored a new playbook for life sciences R&D. Founded in 1989, Vertex's rollercoaster story is most iconically characterized by the rise and fall of Incivek, a hepatitis C drug that reached $1 billion in sales faster than any before it, only to be withdrawn from the market just three years afte ...

The research service features daily updates of the Zacks Rank and Zacks Industry Rank, full access to the Zacks #1 Rank List, Equity Research reports, and Premium stock screens, all of which will help you become a smarter, more confident investor. For new and old investors, taking full advantage of the stock market and investing with confidence are common goals. Zacks Premium provides lots of different ways to do both. It also includes access to the Zacks Style Scores. What are the Zacks Style Scores? The Z ...

The biotech's shares dropped following its latest quarterly update, but that shouldn't matter to long-term investors.There are several textbook arguments against monopolies. According to one of them, companies that control a market can lower the quality of their products with impunity.However, Vertex Pharmaceuticals (VRTX 0.91%), a drugmaker with a monopoly in the cystic fibrosis (CF) market, hasn't done that -- quite the contrary. Since it launched its first CF product some 12 years ago, the biotech hasn't ...

For the quarter ended March 2024, Vertex Pharmaceuticals (VRTX) reported revenue of $2.69 billion, up 13.3% over the same period last year. EPS came in at $4.76, compared to $3.05 in the year-ago quarter.The reported revenue compares to the Zacks Consensus Estimate of $2.56 billion, representing a surprise of +5.15%. The company delivered an EPS surprise of +16.10%, with the consensus EPS estimate being $4.10.While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- ...

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 ________________________________________________________ FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE QUARTERLY PERIOD ENDED MARCH 31, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission file number 000-19319 ____________________________________________ Vertex Pharma ...