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Merck could lose up to $630 million in revenue after CDC changes HPV vaccine recommendation
MarketWatch· 2026-01-08 01:36
Merck could lose up to $630 million in Gardasil revenue this year now that the U.S. no longer recommends three doses of the HPV shot in the childhood vaccine schedule, according to Jefferies analysts. ...
Dr. Rasha Kelej, CEO of Merck Foundation, Named One of ‘100 Most Influential Africans 2025' Alongside Presidents of Angola, South Africa, and Ghana by New African Magazine, UK
Businesswire· 2026-01-08 00:47
DUBAI, United Arab Emirates--(BUSINESS WIRE)-- #100MostInfluentialAfricans--Dr. Rasha Kelej, CEO of Merck Foundation, has been recognized as one of the 100 Most Influential Africans by New African Magazine (UK). ...
默沙东完成收购Cidara Therapeutics
金融界· 2026-01-07 20:13
默沙东公司1月7日宣布,其子公司已成功完成对Cidara Therapeutics公司全部流通普通股的现金要约收 购。2025年11月,默沙东与Cidara达成最终协议。根据协议,默沙东将通过子公司以每股221.50美元现 金收购Cidara,交易总金额约达92亿美元。(智通财经) ...
Quant Q&A With Steven Cress
Seeking Alpha· 2026-01-07 20:00
Credo Technology (CRDO) 的动量评级 - 尽管Credo Technology近期表现停滞,但其动量评级仍为A+,主要基于其相对于板块的长期强劲表现[6] - 在评估动量的四个时间周期内,Credo Technology均跑赢板块:过去12个月股价上涨101%,而板块仅上涨0.36%;过去9个月上涨232%,板块上涨15%;过去6个月上涨60%,板块下跌0.33%;过去3个月下跌4.28%,但板块跌幅更大,为6.39%[7] 量化分析中的Z分数 - Z分数用于评估公司财务指标(如市盈率、收入增长、每股收益增长、EBITDA增长)相对于行业平均或中位数的表现,其值通常在正负3之间[8] - 该量化系统将Z分数转换为从A+到F的学术字母等级,以便投资者快速判断某项指标在行业中的强弱位置[9][10] 默克(MRK)与辉瑞(PFE)的比较 - 在量化评级中,默克在行业179只股票中排名第5,辉瑞排名第7,默克略微领先[13] - 从量化因子等级看,辉瑞在估值(A级)和增长(A+级)上优于默克(估值B-,增长A-),但默克在动量(B-级)上显著优于辉瑞(C级)[13][14] - 近期股价表现支持了默克的动量优势:过去一个月默克上涨10.4%,辉瑞下跌2%;过去三个月默克上涨23.5%,辉瑞下跌5.5%;过去六个月默克上涨37%,辉瑞上涨4%[15] 能源股与估值动态 - 能源股(如Energy Transfer)的估值和评级对油价高度敏感,油价下跌会拖累相关股票的基本面和评级,导致其从“强力买入”降级为“持有”[16][17][18] - 能源行业内不同子行业(如上游、下游、综合一体化、炼油厂)对油价的敏感度不同,并非完全同步[18] - 能源需求与经济周期紧密相关,经济疲软会降低对油气需求,从而影响能源股表现[19] Comfort Systems USA (FIX) 的持有评级分析 - Comfort Systems USA的持有评级主要因其估值因子为F级,尽管其增长(A+)、盈利能力(A-)、动量(A+)和每股收益修正(A-)均表现强劲[23] - 公司估值过高:其追踪市盈率为42倍,行业为21倍;远期市盈率为38倍,行业为20倍[24] - 除市盈率与增长率之比(PEG Ratio)为A-外,其他所有估值指标(如EV/EBITDA、市销率、市净率等)评级均为D或F[25] 投资组合管理与多元化策略 - 量化投资策略强调多元化以最小化风险,建议单一股票头寸不超过投资组合的10%至15%,若超过则需减仓至10%左右[27][43] - 对于已上涨且评级降至“持有”的股票,只要不降至“卖出”或“强力卖出”,且能提供良好股息收益率,通常建议继续持有[20][21] - 在筛选同时具备价值和增长特性的股票时,可使用量化筛选器,要求价值和增长两个因子的等级均在B-或以上[29] 量化系统的评估框架与历史表现 - 该量化系统采用“合理价格增长”(GARP)策略,综合评估价值、增长、盈利能力、动量和每股收益修正五大因子[31] - 每个因子下包含多个加权指标(如价值因子包含市盈率、EV/销售额、市净率、股息收益率等),权重根据指标对未来股价的预测能力进行差异化分配,并非等权重[32][33] - 历史回溯测试显示该策略表现强劲:例如,2024年选出的股票组合若持有至2025年12月10日,回报率达356%,同期标普500指数回报率为47%;2025年组合回报率为25.68%,标普500为17%;2023年组合若持续持有,回报率为187%,标普500为85%[40] 投资纪律与持续投资 - 成功的投资需要坚持纪律,无论市场环境好坏,都应持续定期(如每月或每两周)寻找基本面良好的股票进行投资[42] - 投资者应定期审视投资组合,对大幅上涨且头寸过重的股票进行减仓,并对评级降至“卖出”或“强力卖出”的股票进行清仓[43]
Merck Initiates Phase 3 KANDLELIT-007 Trial Evaluating Calderasib (MK-1084), an Investigational Oral KRAS G12C Inhibitor, in Combination With KEYTRUDA QLEX™ (pembrolizumab and berahyaluronidase alfa-pmph) in Certain Patients With Advanced NSCLC
Businesswire· 2026-01-07 19:50
RAHWAY, N.J.--(BUSINESS WIRE)---- $MRK #MRK--Merck (NYSE: MRK), known as MSD outside of the United States and Canada, today announced the initiation of KANDLELIT-007, a Phase 3 clinical trial evaluating calderasib (MK-1084), an investigational oral selective KRAS G12C inhibitor, in combination with KEYTRUDA QLEXâ"¢ (pembrolizumab and berahyaluronidase alfa-pmph) for the first-line treatment of patients with KRAS G12C-mutant, advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC). This randomi ...
Merck Initiates Phase 3 KANDLELIT-007 Trial Evaluating Calderasib (MK-1084), an Investigational Oral KRAS G12C Inhibitor, in Combination With KEYTRUDA QLEX™ (pembrolizumab and berahyaluronidase alfa-pmph) in Certain Patients With Advanced NSCLC
Businesswire· 2026-01-07 19:50
RAHWAY, N.J.--(BUSINESS WIRE)---- $MRK #MRK--Merck (NYSE: MRK), known as MSD outside of the United States and Canada, today announced the initiation of KANDLELIT-007, a Phase 3 clinical trial evaluating calderasib (MK-1084), an investigational oral selective KRAS G12C inhibitor, in combination with KEYTRUDA QLEXâ"¢ (pembrolizumab and berahyaluronidase alfa-pmph) for the first-line treatment of patients with KRAS G12C-mutant, advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC). This randomi ...
Merck to Complete Acquisition of Cidara Therapeutics
Businesswire· 2026-01-07 19:45
RAHWAY, N.J.--(BUSINESS WIRE)--Merck (NYSE: MRK), known as MSD outside of the United States and Canada, today announced the successful completion of the cash tender offer, through a subsidiary, for all the outstanding shares of common stock of Cidara Therapeutics, Inc. (Nasdaq: CDTX) ("Cidara†). "The acquisition of Cidara strengthens and complements our expanding respiratory portfolio and exemplifies our business development strategy of investing where compelling science and value meet,†said Robert M. Dav ...
Merck to Hold Fourth-Quarter and Full-Year 2025 Sales and Earnings Conference Call Feb. 3
Businesswire· 2026-01-07 19:30
RAHWAY, N.J.--(BUSINESS WIRE)--Merck to Hold Fourth-Quarter and Full-Year 2025 Sales and Earnings Conference Call Feb. 3. ...
Merck & Co.'s Q4 2025 Earnings: What to Expect
Yahoo Finance· 2026-01-06 19:36
Merck & Co., Inc. (MRK), based in Rahway, New Jersey, is a healthcare company. Valued at $264.2 billion by market cap, the company delivers health solutions through its prescription medicines, vaccines, biologic therapies, animal health, and consumer care products, which it markets directly and through its joint ventures. The pharmaceutical giant is expected to announce its fiscal fourth-quarter earnings for 2025 before the market opens on Tuesday, Feb. 3. Ahead of the event, analysts expect MRK to repor ...
115亿美元天价!买了个“配角”:默沙东的清醒,与市场的误读
新浪财经· 2026-01-06 12:30
来源:市场资讯 (来源:求实药社) Sotatercept的早期成绩单确实足以让默沙东挺直腰杆。据财报数据,该药于2024年3月在美国首发,当年 即斩获 4.19亿美元;进入2025年,仅Q2单季度销售额便飙升至 3.36亿美元。这意味着,在上市不足两 年的时间内,它已实质性锁定了"十亿美元重磅炸弹"席位。在近期上市的心血管及罕见病药物中,这种 爬坡速度堪称"梦幻开局"。 2026年1月5日,默沙东宣布欣瑞来®(Sotatercept)在中国获批。这标志着2021年那笔耗资115亿美元收 购Acceleron的交易,终于在全球第二大医药市场完成了监管准入的闭环。 五年前,当默沙东以高溢价押注尚在III期的Sotatercept时,市场争议的核心在于:单一资产的风险敞口 是否过大? 如今,随着该药在美欧日中全面落地,并在上市次年迈向"十亿美元"门槛,默沙东初步验证了其BD团 队对后期资产成药性的判断。然而,剥离掉资本市场的喧嚣,我们需要清醒地认识到:Sotatercept并非 下一个Keytruda,它更像是默沙东在"后K药时代"为平滑专利悬崖而精心配置的一块重要拼图,而非唯 一的救世主。 一、 战略定位修正: ...