交易概览 - Passage Bio与Remix Therapeutics达成最终合并协议，将以全股票交易形式合并，合并后公司将以Remix Therapeutics, Inc.运营，并在纳斯达克以“RMTX”代码交易[1] - 交易已获得双方公司董事会一致批准，预计将于2026年第四季度完成，需满足包括双方股东批准在内的惯例成交条件[6] - 合并完成后，原Passage Bio股东预计将拥有合并后公司约7%的股份，原Remix股东（包括参与融资的投资者）预计将拥有约93%的股份[4] 融资与资金状况 - Remix已获得超额认购的同步私募配售融资承诺，预计将从以德诚资本为首的新投资者财团获得总计约1亿美元的总收益[1] - 包括私募配售收益在内，合并后公司在交易完成时的现金及现金等价物余额预计将足以支持其运营至2028年，并为关键临床里程碑提供资金[2] 公司战略与领导层 - 合并后公司计划由Remix联合创始人兼首席执行官Peter Smith博士领导，Remix董事会成员将成为合并后公司董事，由Matthew Patterson担任主席[7] - 通过此次交易，德诚资本的Peter Colabuono将加入合并后公司董事会[7] - 交易旨在将Remix的RNA处理重编程平台与临床阶段资产相结合，加速为患者提供差异化疗法[3] 核心资产与研发管线 - Remix的主要项目是REM-422，这是一种靶向MYB（一种在多种癌症中起作用、历史上不可成药的转录因子）的口服mRNA降解剂[1] - REM-422目前正处于腺样囊性癌（ACC）以及急性髓系白血病（AML）或高危骨髓增生异常综合征（HR-MDS）的1/2期临床研究中[10] - 美国FDA已授予REM-422治疗ACC和AML的孤儿药资格认定，以及治疗ACC的快速通道资格认定[10] - 合并后公司的资金预计将支持多项REM-422的临床数据读出，包括2027年ACC注册性2期试验数据、AML或HR-MDS的1期试验数据，以及推进Remix的发现管线[2] 交易相关安排 - 作为交易的一部分，将向交易完成时的在册Passage Bio股东分配或有价值权利（CVR），持有人有权按比例获得与Passage Bio对外授权的儿科基因治疗管线资产相关的里程碑付款所实现的部分净收益[4] - 该交易由多家顶级投行提供顾问服务：Latham & Watkins担任Remix法律顾问；高盛、杰富瑞和Evercore ISI担任私募配售代理；RBC Capital Markets和Canaccord Genuity担任资本市场顾问；Cooley担任配售代理法律顾问；Fenwick & West担任Passage Bio法律顾问；Wedbush Securities担任独家财务顾问[8] 公司背景 - Remix Therapeutics是一家临床阶段生物技术公司，致力于开发旨在重编程RNA处理、从根源解决疾病驱动因素的新型小分子疗法，其REMaster™技术平台用于识别调节基因表达的口服化合物[11] - Passage Bio是一家临床阶段基因药物公司，专注于开发治疗神经退行性疾病的一次性疗法，其主要候选产品PBFT02旨在通过提升颗粒蛋白前体水平来治疗额颞叶痴呆等疾病[12]

Oil-Dri sales representatives will communicate specific details of the price increase to their customers directly. About Oil-Dri Corporation of America These pricing adjustments are in response to significant increases in costs outside of the company's control, including health insurance, freight, and resin-based packaging, among others. Daniel S. Jaffee, President and Chief Executive Officer stated, "We are mindful of the effect price increases have on our customers, and we do not make these decisions with ...

Dieppe, New Brunswick--(Newsfile Corp. - June 24, 2026) - Canadian Gold Resources Ltd. (TSXV: CAN) ("Canadian Gold" or the "Company") is pleased to announce the voting results from its Annual and Special Meeting of Shareholders (the "Meeting") held on June 19, 2026 in Dieppe, New Brunswick.The below individuals were nominated and received the requisite majority of votes and will be directors of the Company for the ensuing year:Ronald J. Goguen Sr.Kenneth CherninRoger BourgaultIan McGavneyDavid J. HennigarI ...

To Participate in the Telephone Conference Call:Dial in at least 5 minutes prior to start timeDomestic: 1-833- 461-5787International: 1-585-542-9983Conference ID: 338 306 020 About Century Communities:Century Communities, Inc. (NYSE: CCS) is one of the nation's largest homebuilders and a recognized industry leader in online home sales. Newsweek has named the Company one of America's Most Trustworthy Companies for four consecutive years. Century Communities has also been designated as one of U.S. News & Worl ...

No new commercial formulary additions or coverage decisions issued for neffy (epinephrine nasal spray) in the July 1, 2026 cycle; company to continue payer discussions for potential future inclusion Total 2026 cash-based operating expenses, excluding COGS, lowered to $248 million, reflecting lower second- half spending and continued investment discipline Company reaffirms neffy base business supports a path to cash-flow breakeven in 2027 Phase 2b chronic spontaneous urticaria (CSU) program interim data read ...

Alaska Communications Appoints New Chief Executive Officer Jun 24, 2026 4:05 PM Eastern Daylight Time Alaska Communications Appoints New Chief Executive Officer Share Pictured: Courtland Madock Download media ANCHORAGE, Alaska--(BUSINESS WIRE)-- Alaska Communications today announced that its Board of Directors has appointed Courtland Madock as President and CEO, effective September 1, 2026. Madock succeeds Paul Fenaroli who is stepping down as President and CEO in August to focus on his family. Fenaroli wil ...

公司业务动态 - Spok Holdings, Inc. 宣布已达成协议，将出售其双向寻呼库存中的某些窄带频谱许可证 [1] - 购买方为Sensus USA，该公司是为全球市政和工业市场设计和制造计量及自动抄表产品的企业 [1] - 交易购买价格为800万美元，其中部分对价将递延至现有Spok用户迁移完成后支付 [1] 公司及交易方背景 - Spok Holdings, Inc. 是一家在纳斯达克上市的公司，股票代码为SPOK，是医疗保健通信领域的全球领导者 [1] - 交易涉及出售的资产为该公司双向寻呼库存中的窄带频谱许可证 [1]

行业观点 - 投资者目前认识到持有航天领域股票具有极高的波动性这一现实 [1]

市场整体表现 - 标普500指数下跌5.86点，跌幅0.08%，收于7,358.72点 [4][6] - 纳斯达克综合指数下跌104.58点，跌幅0.41%，收于25,482.46点 [4][6] - 道琼斯工业平均指数上涨187.97点，涨幅0.36%，收于51,854.81点 [4][6] - 本周市场下跌导致纳斯达克100指数市值蒸发超过1万亿美元 [6] 行业板块动态 - 标普500客运航空公司指数上涨 [1][6] - 科技股下跌，加剧了对芯片制造商的关注 [1][6] - 油价跌至伊朗战争开始以来的最低水平，因更多油轮预计将离开霍尔木兹海峡 [6] - 房屋建筑商板块飙升，此前特朗普取消了一项旨在加快经济适用房供应的两党立法签署计划，Hovnanian Enterprises、PulteGroup和Toll Brothers股价均上涨 [4][6] 重点公司动向 - 芯片制造商美光科技股价在2026年飙升超过200%后，于周三下跌，市场关注其盘后公布的业绩 [6] - 芯片设计公司Cerebras Systems在上市后的首份报告中预测全年利润率将低于第一季度数据后股价大跌 [6] - 汽车租赁公司赫兹股价大跌，因公司预计第二季度调整后核心收益接近其预测区间的低端，并宣布计划发行1亿美元普通股 [5][6] - OpenAI宣布推出名为Jalapeno的自研推理芯片，这对相关股票构成压力 [6] 市场情绪与宏观因素 - 对超大规模企业债务支持支出的担忧以及对美联储更加鹰派的担忧加剧，共同推动了本周市场下跌 [3][6] - 交易员正在增加对美联储在12月底前进行第二次加息的押注，此前市场预期仅加息25个基点一次 [5][6] - 美联储偏爱的通胀指标——个人消费支出价格指数将于周四公布，可能为货币政策路径提供线索 [6] - 有观点认为，中东局势讨论接近尾声，能源价格回落，但人工智能资本支出建设仍在继续，市场青睐支出的接受方，却惩罚进行支出的公司 [3][6]

Presentation Hello, and welcome to the Energy Fuels Inc. 2026 Annual Meeting of Shareholders. Please note that this meeting is being recorded. [Operator Instructions]. Bruce Hansen I serve as the Chair of the Energy Fuels Board of Directors, and I will act as Chair of this meeting. Corporate Counsel and Corporate Secretary of the company, Julia Hoffmeier, will act as Secretary of the meeting. Also with us today are Ross Bhappu, our President and Chief Executive Officer; Curtis Moore, Senior Vice President o ...